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为解决食管支架临床使用中易发生滑移的问题，基于纬编针织工艺，以镍钛合金丝为原料，设计制备了由支架主体与两端防滑移圈组成的抗滑移食管支架。系统探究了热定型温度（500、550和600 ℃）与时间（5、15和25 min）对支架径向支撑性能的影响，以及防滑移圈直径（3、4、5和6 mm）与固定位置（端口处、距端口1 cm）对支架抗滑移性能的影响。结果表明：最优热定型参数为温度550 ℃、时间15 min，该工艺下制备的支架的压缩强力超80 cN，弹性回复率接近100%；防滑移圈固定于距端口1 cm时，直径为4 mm和5 mm的支架抗滑移力分别达（10.3±0.8）N和（11.0±0.9）N，较未加装防滑移圈组提升超2倍。研究验证了“支架主体+防滑移圈”结构设计的有效性，所制备的支架在保持优良径向支撑性能的同时，抗滑移能力显著增强，能够满足食管支架的临床使用要求。
Abstract：To address the issue of stent migration in clinical application of esophageal stents， an anti-migration esophageal stent composed of a main body and anti-migration coils at both ends was designed and fabricated using nitinol wire based on weft knitting technology. The effects of heat setting temperature (500， 550 and 600 ℃) and time (5， 15 and 25 min) on the radial compressed performance of the stent， as well as the effects of anti-migration coil diameter (3， 4， 5 and 6 mm) and fixation position (at the edge， 1 cm from the edge) on the anti-migration performance were systematically investigated. The results showed that the optimal heat setting parameters were 550 ℃for 15 min， under which the compression force of the prepared stent was more than 80 cN and the elastic recovery rate approached 100%. When the anti-migration coils were fixed at 1 cm from the edge， stents with coil diameters of 4 mm and 5 mm achieved anti-migration forces of (10.3±0.8) N and ( 11.0±0.9 )N， respectively， which were more than twice that of the group without anti-migration coils. The effectiveness of the “stent body with anti-migration coil” structural design was validated. The prepared stent significantly enhances anti-migration capability while maintaining excellent radial compressed performance， meeting the clinical requirements for esophageal stents.
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基本信息:
中图分类号:R571;TS184.112
引用信息:
[1]陶慧,代曼曼,华语妍,等.抗滑移食管支架的制备工艺及力学性能探究[J].国际纺织导报().
2026-09-22
2026-09-22
2026-09-22